“
“The potential Selleck SHP099 risks of deep hypothermic circulatory arrest in aortic

arch surgery have been well documented. Antegrade cerebral perfusion may ameliorate brain injury but still involves variable periods of cerebral and visceral ischaemia. We describe a novel “branch-first continuous perfusion” technique which avoids both deep hypothermia and circulatory arrest. This brings us closer to the goal of arch surgery without cerebral or visceral ischaemia and the morbidity of deep hypothermia. (Heart, Lung and Circulation 2011;20:163-169) Crown Copyright (C) 2010 Published by Elsevier Inc. on behalf of Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand. All rights reserved.”
“ObjectiveThis study aims to estimate the incidence of adverse events (AEs) and avoidable AE in four hospital services before and after applying strategies for patient safety.\n\nDesignRetrospective study of two cohorts (2006 and 2009).\n\nSettingGeneral Surgery, Internal Medicine, Intensive Care Unit and Oncology services.\n\nParticipantsA sample of 365 patients (2006) and 232 in 2009 randomly selected from the services previously cited.\n\nInterventionsStrategies to improve patient safety (e.g. hand-hygiene

campaign).\n\nMain GSK2118436 purchase outcome measuresAnalyses were made of the change in the incidence and type of AE and avoidable AE, number of procedures and additional days of hospital stay, and the concordance between two recording systems.\n\nResultsThe incidence of buy Crenigacestat patients with AE was 20.8% in 2006 compared with 28.9% in 2009 (P<0.05). Oncology had twofold more AE than did General Surgery [odds ratio (OR)=2.07, 95% confidence interval (CI): 1.12-3.86] for the same length of stay

and number of extrinsic risk factors. In 2006, 84.6% were considered avoidable, compared with 57.1% of 2009 (P<0.001). There was no difference in the average length of additional stay. In 2006, there were more additional procedures compared to 2009 (OR=2.75, 95% CI: 1.28-6.06). A concordance of 61% was found for the detection of AE with the two recording systems.\n\nConclusionsAn increased incidence in AEs was found after the strategies, while avoidable AE decreased, as did additional treatments and procedures. The measures implemented constitute a further step in reducing avoidance and a greater awareness of recording AEs in the discharge report.”
“Objectives: In this literature review, we concentrate on epidemiology and therapy of osseous echinococcosis, with an emphasis on the recurrence risk. Methods: Literature review 1930-2012. Results: We retrieved 200 publications based upon single case reports or case series, mostly from resource-poor settings. Among the 721 rural patients (22% females; median age 37 years), 60% of all reported cases were from the Mediterranean region and almost all patients were immune competent. Echinococcus granulosus was identified as the most frequent species.