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SA, Schmalz G, Hiller KA, Troxler RF: Proteins in whole saliva during the first year GDC 0068 of infancy. J Dent Res 2005, 84:29–34.PubMedCrossRef Competing interests OH is member of the scientific advisory board of Semper AB. Authors’ contributions IJ, MD, OH, ACRT planned, designed and financed the study. NT coordinated and organized infant participation and sampling. NRV, and PLH coordinated the oral part of the study. NRV, CÖ, CK (qPCR experiments), RC (microbiological identifications) performed laboratory experiments. NRV and IJ performed statistics and drafted the manuscript. All authors contributed to completion of the manuscript and approved it.”
“Background Growing concern over the increase in multidrug resistant bacteria has urged the interest for development of new L-NAME HCl types and classes of antimicrobial compounds. One such class is antimicrobial peptides (AMPs), also known as host defence peptides, that are found in all multicellular organisms and form an important part of the innate immune system [1]. They exhibit antimicrobial activity against a wide range of pathogenic microorganisms, have immune-modulatory effects and enhance the host defence against pathogenic bacteria [2–4]. AMPs are usually small cationic and amphiphatic peptides comprised of less than 40 amino acids with immense diversity in sequence, secondary structure motifs, charge and/or the abundance of certain specific amino acids [5].