Complete edentulism prior to 65 years of age Lapatinib was associated with all-cause mortality after multivariable adjustment for several socioeconomic characteristics over a 16-year follow-up period [54]. Tooth loss is a significant predictor of mortality independent of health factors, socio-economic status, and lifestyle in octogenarians, with a stronger association in women [55]. In a survey of a population of 80-year-old community residents, the ability to chew the fewest types of food was associated with a higher risk of mortality than that of those with the ability to chew all 15 types of food [56]. Self-assessed masticatory

disability remained a significant predictor of 9-year mortality in a cohort of community-residing older adults [57]. Survey respondents find more reporting the lowest number of chewable foods were associated with a higher risk of cardiovascular mortality than those who were able to chew all types of food in a prospective study of 697 80-year-olds [58]. Women aged 40 years or older with fewer than 10 functional teeth and without

dentures showed a significantly higher mortality rate than those with dentures during a 15-year follow-up period [59]. In healthy independent older adults aged 65 or over, poor dental occlusion was associated with an increased risk of mortality; in the edentulous, and the use of dentures was associated with a decreased risk of mortality [60]. Denture use was shown to be a significant indicator of perceived chewing ability in older adults without occluding pairs of natural teeth [61]. These findings suggest that poor dentition status, the lack of denture use in a person with few natural teeth, and impaired masticatory ability may be significant factors associated with increased mortality. (1) Masticatory function is significantly associated with nutritional intake and status at the early stage of ageing medroxyprogesterone adults. Other influencing factors should

be considered to approach nutritional problems as well. The authors have no conflicts of interest to declare. “
“2014 marks the start of the 31st year of the ancient Chinese sexagenary cycle. This year’s term appears to represent a wide-jumping horse, and it is also said that people who were born during the 31st year of the cycle thrive like large trees in midsummer. There are expectations for any type of large changes in this year. However, I think it is more suitable for the year to leap into action and get results rather than waiting for changes to occur. So how should the dental industry “leap” forward? The keyword of JADS executives is revitalization. First and foremost, it is necessary for the dental industry to create a definite theme which enables us to come together toward the aim of matching the expectations of citizens and society. From the start, we need to be highly responsive in order to grasp the demands of society. Then, the dental industry should respond by aiming for a theme that creates social opportunities and social atmosphere.