“
“Objective The aim of this study was to assess validity, reliability, and

sensitivity of the Persian version of the short-form McGill Pain Questionnaire 2 (SF-MPQ-2) in patients with neuropathic and non-neuropathic pain. Design Beaton’s guideline was used to translate and adapt the SF-MPQ-2 to Persian. Subjects One hundred eighty-four patients with subacute and chronic non-neuropathic pain and 74 patients Dorsomorphin in vivo with painful diabetic peripheral neuropathy (total 258) attending multidisciplinary pain clinic participated in the study. Outcome Measures Internal consistency and intraclass correlation coefficient (ICC) were estimated for participants who had completed the questionnaire in the morning and evening of the first day. The visual analog scale (VAS) and the present pain intensity (PPI) were also recorded to test convergent validity of the questionnaire. Sensitivity to change was examined after a standard treatment and validated by means of the patient global impression of change (PGIC) in addition to VAS and PPI. Exploratory factor analysis (EFA) was used to find possible components. Results Cronbach’s alpha was 0.906, which showed high internal consistency. ICC (0.941) revealed testretest reliability. There was high correlation between the mean VAS and the mean total score (r?=?0.926). Patients in different levels

of PPI and PGIC exhibited significant differences among their mean total scores (P?<?0.05). EFA revealed four components similar to the original SF-MPQ-2. Conclusion The Persian translation of the expanded and revised version of the SF-MPQ-2

ERK inhibitors high throughput screening is a highly reliable, sensitive, and valid instrument to evaluate pain in patients with and without neuropathic etiology.”
“Objectives To determine the differences in pain, disability, depression, and pressure sensitivity between men and women with fibromyalgia syndrome (FMS), and to analyze the relationship between pain and pressure sensitivity in FMS. Design A cross-sectional study. Setting Gender differences in pain sensitivity in individuals with FMS have not been yet clarified. Patients Twenty-four men (age: 52?+/-?6 years) and 24 age-matched women (age: 52?+/-?5 years) with FMS diagnosed according to 1990 American College of Rheumatology criteria participated. Outcome Measures Pressure pain thresholds (PPTs) over the 18 tender points and over the second metacarpal AG-881 research buy and tibialis anterior muscle were assessed. The intensity and duration of pain, tender point count, the Fibromyalgia Impact Questionnaire, and depression (Beck Depression Inventory-II) were calculated. Results Women reported higher intensity of pain, tender point count, and depression than men (P?<?0.01). Men reported a longer history of pain and disability than women (P?=?0.005). Women showed bilateral lower PPT over suboccipital, cervical spine, second rib, supraspinatus, lateral epicondyle, gluteal region, and second metacarpal than men (P?<?0.05).