Asymptomatic hyperuricemia (HU) is common in the population and substantially plays a part in the overall cardiovascular danger. Despite substantial research for this problem there is however no conclusive responses to questions regarding recognition of asymptomatic HU and its own impact on the danger for development and progression of aerobic and kidney diseases. This analysis summarizes crucial information on Biomass pretreatment these problems, which has been built up by the present time.The article compares two analytical methods, which are commonly used in present comparative scientific studies, a hypothesis that a drug is superior over another one (superiority) and a hypothesis that a drug is not inferior incomparison to a different one into the effectiveness and security (non-inferiority). Utilizing the example of specific researches, the difference between the methods and also the tasks, for the answer of what type or any other strategy must certanly be used, are shown. To be able to show the superiority in efficacy and protection of a new medication over an existing one, just a statistical strategy that utilizes the “superiority” hypothesis is relevant. Studies using the “non-inferiority” theory are employed for researching drugs, that are not dramatically different within their effectiveness, but the research medicine features various other benefits within the administration, storage, tolerability etc. The choice of statistical method is decided exclusively by the task associated with study.This review is targeted on the relevance of sinus rhythm control in patients with atrial fibrillation in real-life clinical training and certain medical popular features of clients with this specific arrhythmia. The authors presented current directions on prevention of thromboembolic complications and overview of outcomes from significant medical researches of direct dental anticoagulants. The research literary works and variety of medical researches for 2009-2020 had been performed on websites regarding the European and Russian Societies of Cardiology, the All-Russian Scientific Society of Arrhythmologists, and in online databases PubMed, EMBASE, eLibrary, and Google Scholar with the key words atrial fibrillation, anticoagulants, ablation, cardioversion, and efficacy and safety.Aim Patients with heart failure with minimal left ventricular (LV) ejection fraction (HFrEF) who may have had severe myocardial infarction have actually an unfavorable prognosis, largely because of ventricular arrhythmias (VA) and threat of abrupt cardiac death (SCD). The optimal therapy (triple neurohormonal blockade plus implantable cardioverter defibrillator and cardiac resynchronization therapy) reduced the risk of SCD primarily due to reverse cardiac remodeling, but has not yet resolved this dilemma completely. Efficacy of purified ω-3 polyunsaturated fatty acid esters (PUFA) in reasonable amounts (1 g/day) in reducing VA and chance of SCD in HFrEF clients had been shown in two big randomized medical trials. The PUFA impacts had been suggested is related also with additional heart rhythm variability (HRV) and chronotropic activity, which could rely on the drug dose. The current available, prospective, randomized, relative study in synchronous groups assessed the result of Omacor in numerous doses on noninvasive markers of SCD risk in patiease in LV EF ended up being considerable just with the employment of Omacor 2 g/day (+3 %, р=0.002). An adverse chronotropic effect of ω-3 PUFA ended up being seen. Average 24-h hour diminished by 8 bpm (р=0.05) and 11 bpm (р<0.001) with Omacor 1 g/day and 2 g/day, correspondingly. Either dose of ω-3 PUFA somewhat enhanced VO2, which straight correlated with LV EF and inversely correlated with HR. The decrease in range VE ended up being associated not only with improved HRV (SDNN) but additionally utilizing the reduction in 24-h HR, and thus Omacor 2 g/day somewhat decreased the sheer number of VE (by 16 per hour) and dangerous VA (paired VE and VT runs ceased to be recognized in 40 % of patients).Conclusion Since HR, HRV, and VA are closely interrelated, the result of ω-3 PUFA particularly on these noninvasive markers evidently determines being able to reduce the chance of SCD in clients with ischemic HFrEF. The antiarrhythmic effectation of Omacor was greater with higher amounts of this drug.Aim to analyze ultrasonic characteristics of lung structure in clients with heart failure with left Next Gen Sequencing ventricular (LV) mid-range ejection fraction (HFmEF) and predictive worth of these attributes after reversing severe decompensated heart failure (ADHF).Material and techniques Ultrasonic attributes of lung muscle were studied by potential observation in 71 customers (mean age, 65.2±3.6 many years; men, 64.3 %) with HFmEF (LVEF from 40 to 49 %) after ADHF reversal. Semiquantitative analysis of B-lines was performed because of the E. Picano (2016) method at 5+2 times after hospitalization as well as on discharge through the hospital. The distance between B-lines was 3 mm (В3 lines) and 7 mm (В7 outlines). Patients’ catamnesis ended up being examined for identifying the predictive value of lung tissue ultrasonic qualities for two years considering that the list hospitalization. Analytical analysis had been carried out utilising the McNemar’s χ2 test (for evaluation of linked samples as well as changes in the presence/absence of B-lines as dependant on lung ult%.Conclusion “Ultrasonic pulmonary edema syndrome” in customers with LV mid-range ejection fraction after reversing ADHF was characterized by predomination associated with the interstitial element, regardless of the lack of X-ray obstruction, correlated utilizing the Cetuximab molecular weight bloodstream standard of NT-proBNP measured at precisely the same time, and had been related to rehospitalizations.Aim to review the association between concentrations of endothelial dysfunction (ED) markers and arterial hypertension (AH) in those who were exposed to long-lasting activity of “low-dose” ionizing radiation.Material and methods the research topics had been men of middle-age (45-55 years) who have been workers of this Siberian Integrated Chemical Plant using the length of service on the shop floor of at least five years.