Proc Natl Acad Sci USA 2005,102(43):15545–15550.PubMedCrossRef 32. McAleese F, Petersen P, Ruzin A, Dunman PM, Murphy E, Projan SJ, Bradford PA: A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline. Antimicrobial agents and chemotherapy 2005,49(5):1865–1871.PubMedCrossRef Authors’ contributions ŠB performed the microarray experiment, participated in study design, data interpretation and helped

to draft the manuscript. MP participated in data analysis (GSEA, Pathway Studio visualization), performed the qPCR analysis, interpreted the data, and drafted the manuscript. DK participated in the design of the study, sample

QNZ preparation and data analysis (GSEA, pathway visualization). AR performed the statistical analysis. ZP participated in study design, data interpretation and drafting the manuscript. KG participated in the design of the study and data interpretation, coordinated the work and helped to draft the manuscript. MR and UU participated in the design of the study and helped to draft the manuscript. All authors read and approved the final manuscript.”
“Background Olive knot disease is a plant disease characterized by hyperplastic symptoms mainly on twigs, young branches and the trunk, 2-hydroxyphytanoyl-CoA lyase more rarely on leaves and fruits,

of olive trees (Olea europaea L.), which exists worldwide wherever this crop is cultivated. histone deacetylase activity This disease is particularly damaging as far as quantitative and qualitative production is concerned [1, 2], and causes heavy losses in the countries of the Mediterranean basin where olive plants are extensively cultivated. The causal agent is the plant pathogenic bacterium Pseudomonas savastanoi pv. savastanoi (Psv) [3, 4], isolated and described for the first time by Luigi Savastano [5, 6]. Psv enters and infects plants generally through wounds of different origin (i.e. HSP990 nmr pruning and mechanical wounds, frost injuries, leaf scars) [7]. The pathological process depends on the expression of bacterial hrp genes [8], and the development of the spherical knots is caused by phytohormones (3-indoleacetic acid and cytokinins) synthesized by Psv, that trigger uncontrolled proliferation of the cells surrounding the site of infection [9–13]. In the species P. savastanoi were also included isolates from oleander (Nerium oleander L.), ash (Fraxinus excelsior L.) and other plants, such as privet (Ligustrum japonicum Thunb.), Jasminum spp. and Retama sphaerocarpa (Boiss.) L., and the taxonomy and the classification of this bacterium have been controversial for a long time.